No

Name of the deliverable

Lead Beneficiary

SOP - Strategy - Guidance document

D4.01

Initiate and perform in-life long-term inhalation study

3

 

D4.02

Provide histological samples from chronic study

3

 

D4.03

Lung burden and particle detection and quantification in olfactory bulbs, blood- subacute exposure

3

 

D4.04

Organ burden and particle detection pattern in other organs after subacute exposure

6

 

D4.05

Lung burden and particle detection and quantification in olfactory bulbs - chronic exposure

6

 

D4.06

Organ burden, faeces analyses and particle detection pattern in other organs after chronic exposure

6

 

D4.07

Histopathological evaluation (all organs) Immunohistochemical detection of local and systemic genotoxicity

3

 

D4.08

Quantification of absorption and determination of systemic MNM distribution

 

this deliverable has been skipped

D4.09

In vivo results on genotoxicity and biological markers

 

this deliverable has been skipped

D4.10

Particle distribution of MNM in hepatic and liver cell models

6

 

D4.11

Identification of hazards and NOAELs for amorphous silica after subchronic oral exposure

17

 

D4.12

Accumulation potential and aquatic toxicity of relevant groups of nanomaterials and product formula

51

SOPs available in Deliverable:

  • SOP 01 Toxicity Test with Daphnia magna for NANoREG core nanomaterials
  • SOP 02 Toxicity Test with Microalgae Pseudokirchneriella subcapitata
  • SOP 03 Toxicity test with the nematode Caenorhabditis elegans
  • SOP 04 Fish, Acute Toxicity Test

Extra SOP developed within WP2 for ecotoxicological testing:

NANoREG D4.12 SOP Probe Sonicator Calibration for ecotoxicological testing

D4.13

Mode of toxic action of high aspect ratio nanomaterials

4

 

D4.14

Prenatal toxicity study with cerium oxide and MWCNT carbon nanotubes

28

 

D4.15

Protocol for inhalation exposure and choice of biological relevant endpoints

34

 

D4.16

Immunotoxic and genotoxic effects  after short-term inhalation of fibrous nanomaterials

57

 

D4.17

Development of PBPK models

15

 

D4.18

Overall evaluation of data, publication, and transfer to OECD sponsorship programme

3

 

If not indicated otherwise, the information in the NANoREG Results Repository is available under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Information on “commercial use” and attribution can be found here.