Abstract

A cross-sectional serological survey involving 355 children was performed to study the immunogenicity of DPT-IPV vaccine and measles vaccine under tropical conditions. The vaccines were used in the EPI programme in three provinces in Burkina Faso, West-Africa. A two dose regimen is followed for DPT-IPV. A very high percentage of the group of 179 twice vaccinated children was antibody positive. In the 176 non-vaccinated children a substantial proportion had antibodies to polioviruses, most of them only to one type. This appears to be a sensitive parameter for the circulation of wild polio viruses in the environment.